4.Estructura and function of the rough endoplasmic reticulum
It is a group of flattened sacs and interconnected membranous tubules and the karyotheca. Their membranes are covered on its outer surface or cytosolic side by ribosomes, these being attached by its largest subunit. The functions of the RER are; intracellular movement of substances are not released into the cytoplasm, protein synthesis, which takes place on ribosomes attached to their membranes, another function is the pipeline and processing of proteins that go to different destinations within or outside the cell. The proteins that are produced in the RER are several types: hydrolytic enzymes, which will form part of the lysosomes and protein secretion, RER is well developed in cells with high secretory activity of proteins that make antibodies, pancreatic cells producing digestive enzymes, etc.
The membrane of the RER has a specific receptor to which the riboforina joins the polyribosome, this receiver is not possessed by the REL does not bind ribosomes to this organelle. The RER is a fundamental part of the secretory pathway
