Blood tissue

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Sanguine tjido: prliminar note: poblacions clulars librs: cells; q no s associated to form 1 set coernt, dtrminado topograficamnt and rlativamnt well circumscribed. notic s st grouped under globuls d ls ls blood and cells; inm1comptnts. abla d s also sist + cells; diffuse s DCIR, distribui2 in tji2 ls dl propiamnt dixos agencies. common functional caractristica stas d all cells; s mobility. most cells; d stas s located in the lymph and blood especially. s ls dnomina ocasionalmnt cells; Immigrants. ls poblacions clulars librs s found in: - "tji2" circulants (blood, lymph, LIKIDO cfalo-rakido;-tji2 ematopoyeticos (osa Mdula red Formacions linfoids;-other tji2 (epitlials, conjunctive ..) inm1comptnts d ls sistma immune cells; , involved in mcanismos d ls dfnsa spcificos s settling in: the bear Mdula ematopoyetica, blood and lymph, ls .. linfoids Formacions ematopoysis embryonic and postnatal FTAL: ls the ematopoysis Sucden tji2 and organs in ematopoyeticos. existn adult animal enl 2 ematopoyetica activity foci d: l tjido honey, located in osa l tjido Mdula lymph organs and intgrant d ls Formacions linfoids. during embryonic and FTAL distinguish the 3 prio2 dntro ematopoysis d: 1.) prepatico or msnkimal: spend notif sman duodcima ls dl sgunda and dsarroyo umano. lslmntos sanguinhos s msnkima dl difrncian from the sac lining extraembryonic Vitlin q, where s is StarSmasher d ls wolff and Pandro. 2.) Epata-lymphocytes: ac his appearance sgundo ms twitch dsarroyo umano dl nivl dl to IGAD, spleen, thymus and lymph nodes. s gnranlmntos d ls all SIRS. the formation d blood is being replaced, and DSDL's sixth paulatinamnt ms, x the bear Mdula. 3.) Mdula-lymphocytes: s implanted into the bear Mdula DSDL dsarroyo dl's sixth ms. ls dífrnts blood prcursors d d aparcn dntro entrmzcla2 Mdula bear the red: tjido honey frame d-q rticles sustnta to conjunctive cells; d ls ls Sanguine divrsas SIRS. -adipocytes in varying amounts. d-capilars sanguinhos lucs endotlio large and discontinuous and sinuous to rid lslmntos qs ls mature. ematopoyetica comptnt clul madr: s dtrminada clul msnkimal comptnt and the formation xa d cells; compromtidas in difrnciacion dlmntos prtn100ts to ls divrsas SIRS: red plaqtaria, mono-granulopoietic, linfopoyetica. d prognie clul the madr pluripotnt dblgir the divrsas notif altrnativas d difrnciacion globulins. d its difrnciacion ants, all cells; Mustra ls 1 x lo q aspcto similar idntificacion with mdios its morphological rsulta impossibility. The 1st exprncia classical existncia d xa dmostrar the cells; madr pluripotncials in osa Mdula consist in:-s x-rays radiate animals, bear d s Mdula transfused donor 1 softw, xa proxcionar the USPD irradiated 1 new tjido ematopoyetico. -1s days after d, s d cells; dsarroyan colonies. s-checked with gnticos Marcadors noduls splnicos ls q sn clons driva2 d 1A clul 1ica founder: the ufc, hese cells; MADRS an d sr. ematopoyetica compromtida clul madr: aqya qa adkiridol s commitment sguir the 1st d d irrvrsibl lina difrnciacion, a1002e x lo 1ipotncial both. st commitment goes sguido d 1A divisions clulars srie d q d cells; rsrva amplify compromtidas madr. ls divisions Somtas to stan d imxtants amplification controls the production q rgulan srie d each. ls cells; madr compromtidas Mdula s are in the bear and organs and Formacions linfoids ls.d rgulacion the ematopoysis: 1.) erythropoietin (Epo): ormone, produced nivl dl q Stimula the eritropoysis kidney. 2.) ormone and other factors similar to erythropoietin: ormone produced rspusta to ncsidads ls, ls rspcto to divrsos types d globuls od plaqtas white. s postulates existncia d 1 glycoprotein umoral factor Xa spcifico each variant d clul prcursora. interleukins humoral factors are also involved in hematopoiesis. 3.) GM-CSF (d stimulant factor granulocyte-macrophage colony d) ls nutrofils granulocytes and ls d 1 macrophages driven prcursor compromtido same or forced. st xa prcursor dpnd its suprvivncia d GM-CSF. ls concntracions d GM-CSF aumntan blood bruscramnt dspus d 1A infccion. 4.) other factors: ormone ipotalamicas, ipofisiarias, suprarrnals, terre and cobalt, vitamin B12 and folic acid. 5.) rtroalimntacion: dlmntos figure mature blood prifrica , q rtroalimntacion conditions mcanismos d frnan Stimula or prcursors the difrnciacion d ls d ls ls in various organs ematopoyeticos SIRS.

blood composition d: 1.) plasma (55-60%) 2.) lmntos forms or globuls: (40-45%) a.) corpusculs: * ematis, globuls red or erythrocytes (4.5-5 miyons / mm 3 in mujrs and 4.5-5.5 miyons / mm 3 in varons) * thrombocytes or plaqtas: (150.000-300.000/mm 3) b.) cells;: globuls white or lucocitos (5.000-7.000 (mm 3) * granulocytes "nutrofils: caya2 = juvnils = band (1-3%) and sgmnta2 (60-70%)-eosinofils (1-3%)-basofils (0.5-1%) * agranulocytes:-lymphocytes ( 20-40%), monocytes (2-6%). funcions blood d: d transxt DSDL intstino nutrients and blood to kilifros ls tji2; dl ls tji2 IGAD and IGAD nuevamnt, d 1 tjido to another. intrcambio d gass rspiratorios notif ls ls and ls Pulmons tji2. transxt products d ls d ls dsxo acia mtabolismo dl riñons, skin, and IGAD intstino xa your excrcion. distribucion d rguladoras ormone and other substances. protccion FRNT microorganisms, dl EKILIBRIO mantnimiento acid-bas e-minral idro. trmorrgulacion, coagulation. dl erythrocyte life cycle: mature erythrocyte: red blood cell: (* concpto and gnralidads): ls erythrocytes ematis ls, sn d corpusculs clulars blood whose main function sl transxt and libration d 0 2 and co 2: ematosis. biconcave discoidal shape s, the q intrcambios gasosa favorc ls, pus rprsnta the rlacion suprficie / volumn optimal. ylasticidad dpndn his mantnimiento dl d Protina citosqlto: spctrina, actin and tropomiosina.l size, in the SPCI umana, sd ? d diamtro maximum 7.8, with 1 d 2? in thickness and 1.5 ? prifria cntro enl. (* res): Very simple: 1a envelope dlimita clul q 1 contnido eosinophilic modradamntlctron-DNSO omogno amorphous, Compustar sncialmnt x emoglobina. carcn d nucl. dtctan s in condicions normals in the circulating blood 1 1% sw rticulocitos: ematis immature even consrvan rstos d q + and other organuls ribosomes, the mo rvla2 cm lumps and 1st rd DLIC basophilic. (* mdia life, dstruccion and rnovacion): life ematis mdia d ls, 1st vz q Mdula leave bear and pass into the blood sd 120 days. dstruccion d ls ematis the old dsgasta2 Sucden DFctuoso and spleen and enl fundamntalmnt Mnor degree, enl IGAD and Mdula own bear, macrophages engulf and CITIES dgradan dond ematis ls, and ls rutilizan2el terre d aminoaci2 the emoglobina, st procs s eritrocatrsis. ematis Sucden d production in procs sgunl Mdula dnominado eritropoysis osa. (* eritropoysis): s begins with Erythropoietic the madr clul q will difrnciars, sucsivamnt in clulars types siguients ls "Pronormoblasts,-erythroblast basophilic erythroblast Polychromatophilic-,-normoblast,-rticulocito,-ematie. mdida qs to difrncian and mature cells; d ls red van srie decreasing its volumn; condnsan nuclear chromatin, till the expulsion stadio d dl normoblast Nuclo enl; incrmntan the sintsis d emoglobina and pierdn their organuls.Life cycle of thrombocytopenia, thrombocytopenia ripe: thrombocytopenia: (* concept and general) are the corpuscles, platelet blood cell involved in hemostasis. Its shape is oval, elongated or discoidal. The size ranges from 2 or 3?. (* Structure) comprises an envelope that defines a compartment corpuscular appearing at mo with a clear halo content. On the periphery is occupied by contractile microfilaments and microtubules and, in the center of granules of various kinds, ribosomes and mitochondria. 2 zones are distinguished: * The hialomero: microtubules and microfilaments. * The granulomero: granules ?, ?, ?-containing membrane-delimited hydrolases, peroxidases, platelet factors 3 and 4, serotonin, calcium, ATP and ADP, catecholamines, etc. .. (* half-life, destruction and renewal): average life platelets once they leave the bone marrow and enter the blood is 4 to 12 days. Old elements, defective and worn are destroyed in the spleen as well as in the liver and bone marrow, the phenomenon is called trombocateresis. Platelet production occurs in the bone marrow according trompoyesis cell from the mother involved.

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