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Monocytes:
It has a size of a bean-shaped nucleus that occupies almost the entire cell.
The monocyte is an immature cell that is in transit in the blood, then goes to the tissues and transforms them into mature macrophages, therefore, macrophages and monocytes are the same cell at different stages of maturation
The functions of monocytes are:
"Phagocytosis and antigen processing
Antigen-presenting cells (APC)
-Production of molecular mediators of the immune response (IL-1, IL-12, TNF, etc.).
"These cells once they pass from the blood as monocytes to tissues, are lodged in them and can take different conformations and functions depending on the tissue where staying, to the point that they can acquire different forms and names as:
- Kupffer cells in liver
- Epithelioid cells in granulomas
- Cells of the microglia in the CNS
- Alveolar macrophages in the lung
- Kidney mesangial cells



Eosinophils
- Fundamentally are stained with acid dyes containing eosin and hence its name.
- The granules stain more red than the rest of granulocytes.
- The eosinophil is a cell rather scarce in the blood and their ratio does not go beyond 3% of total leukocytes.
- Their role is fundamentally anti-parasitic and are able to participate as regulatory cells of the inflammatory process

- The eosinophil granule contains among its various molecules, one of them known as major basic protein (MBP), which is quite toxic and kills parasites.
- Also contains histaminase which neutralises the action of histamine, which is an important component in the processes of inflammation.

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Neutrophils: The main feature is that virtually no granular content stained with the dyes used in MGG, hence the name of neutrophils. (55%)
- Its function is to eliminate all waste produced in the immune response, are capable of emitting pseudopodia engulf, and digest them by incorporating what they have large amounts of enzymes, proteases and myeloperoxidase trigger the respiratory burst


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